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. Author manuscript; available in PMC: 2023 Nov 24.
Published in final edited form as: Curr Res Chem Biol. 2023 Sep 22;3:100045. doi: 10.1016/j.crchbi.2023.100045

Fig. 2. SGC-CLK-1 binds to CLK1, CLK2, and CLK4 in cells (n = 3).

Fig. 2.

The compounds were evaluated in NanoBRET (NB) assay which provides a quantitative measure of in-cell target engagement. For further details and background of NanoBRET assay see references (Vasta et al., 2018; Wells et al., 2020).