Fig. 1.

Experimental setup for the analysis of Ti-DC migration to dLNs after NIR-PIT induction. A Time course and flow diagram of NIR and violet light irradiation of tumor. Twenty-four hours after anti-CD44-IR700 intravenous injection, tumor cell death was induced by NIR irradiation and at the same time, tumor infiltrating KikGR⁺ cells were photoconverted by exposure to violet light. Cells in dLNs were analyzed 24 h later. B KikGR cells were detected in photoconverted and non-photoconverted tumors and inguinal dLNs in KikGR mice immediately after NIR and/or violet light irradiation of tumors. Data are representative of two independent experiments