Fig. 2.

NIR-PIT enhances Ti-DC migration to dLNs but not MoDCs. Anti-CD44-IR700 or vehicle was intravenously administered into tumor-bearing KikGR mice 24 h before the time of NIR light and violet light irradiation of tumor and another 24 h later, cells in dLNs were analyzed. A Representative flow cytometry plots of total migratory, CD103⁺, CD103^–, CD326⁺ and MoDCs in dLNs of Anti-CD44-IR700 or vehicle-treated KikGR mice. B Number of KikGR-Red cells in total migratory DCs, and DC subsets in dLNs. Numbers in parentheses indicate increased multiples to vehicle. Bar graph shows means ± SEM of pooled data from two independent experiments (n = 4–5). *P < 0.05, (Mann–Whitney U test)