Table 2.

Overview of meta-analysis statistics

	2 year OS	5 year OS	2 year DFS	5 year DFS	2 year DSS	5 year DSS	2 year LC	5 year LC
Number of studies (k)	5	4	4	4	2	2	2	2
Log odds ratios (range)	−0.28 to −0.91	−0.25 to 0.56	−0.36 to 0.10	−0.59 to 0.83	−0.25 to 0.56	−0.38 to 0.38	0.07 to 0.88	−0.06 to 0.62
Majority of estimates
Direction	Positive	Negative	Negative	Positive	Positive	Positive	Positive	Positive
% Studies	60%	50%	50%	75%	50%	50%	100%	50%
Estimated average log odds ratio (\hat{\μ})	0.21	0.09	0.22	0.17	0.23	0.08	0.47	0.34
95% confidence interval	−0.24 to −0.67	−0.20 to 0.38	−0.35 to 0.79	−0.42 to 0.77	−0.55 to 1.02	−0.65 to 0.8	−0.33 to 1.26	−0.31 to 0.99
Significance of average outcome
Z score	0.90	0.61	0.74	0.57	0.58	0.21	1.15	1.01
p-Value	0.366	0.542	0.456	0.57	0.56	0.83	0.25	0.31
Maximum weightage
Study	Kang et al.	Kang et al.	Pillai et al.	Pillai et al.	Kang et al.	Kang et al.	Pillai et al.	Mair et al.
% Weight	25.69%	55.07%	29.40%	27.67%	59.5%	60.2%	51.04%	58.6%
Heterogeneity
Q-test	20.85	4.17	8.02	10.34	4.32	4.04	4.09	1.76
tau2	0.20	0.03	0.21	0.26	0.25	0.21	0.25	0.1
I2	80.82%	28.10%	62.57%	71.00%	76.8%	75.2%	75.5%	43.14%
Outliers
Studentised residuals	<  ± 2.57	<  ± 2.50	<  ± 2.50	<  ± 2.50	<  ± 2.07	<  ± 2.01	<  ± 2.02	<  ± 1.3
Studies	None	None	Mair et al.	None	None	None	None	None
Influential studies
Cook’s distances	< 1	< 1	< 1	< 1	> 1	> 1	> 1	> 1
Studies	None	None	None	None	Kang et al.	Kang et al.	Pillai et al.	Mair et al.
Funnel plot asymmetry
Rank correlation p-value	0.82	0.75	1.00	0.75	1.00	1.00	1.00	1.00
Regression test p-value	0.82	0.70	0.99	0.53	0.0016	0.049	0.01	0.08