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. 2023 Jun 5;17(11):1781–1790. doi: 10.1093/ecco-jcc/jjad094

Table 2.

Fatigue measurements in patients with UC/CD compared to the Norwegian general population [NGP].

UC vs. NGP
UC [n = 670] NGP [n = 2287] Mean difference [95% CI] p-value
Mental fatigue 5.15 [1.8] 4.3 [1.4] 1 [0.9, 1.1] <0.001
Physical fatigue 11.42 [4.1] 7.9 [3.1] 4 [3.7, 4.3] <0.001
Total fatigue 16.58 [5.4] 12.2 [4.0] 4 [3.6, 4.4] <0.001
Total fatigue, males 15.49 [5.2] 11.9 [3.9] 4 [3.4, 4.6] <0.001
Total fatigue, females 17.80 [5.3] 12.6 [4.0] 5 [4.4, 5.6] <0.001
Substantial fatigue 403 [60.1] 503 [22] <0.001
Substantial fatigue, males 176 [49.6] -
Substantial fatigue, females 227 [72.1] -
CD vs NGP
CD [n = 313] NGP [n = 2287] Mean difference [95% CI] p-value
Mental fatigue 5.34 [2.0] 4.3 [1.4] 1 [0.8, 1.2] <0.001
Physical fatigue 12.19 [4.2] 7.9 [3.1] 5 [4.5, 5.5] <0.001
Total fatigue 17.53 [5.5] 12.2 [4.0] 5 [4.4, 5.6] <0.001
Total fatigue, males 15.68 [5.2] 11.9 [3.9] 4 [3.1, 4.9] <0.001
Total fatigue, females 18.84 [5.3] 12.6 [4.0] 6 [5.2, 6.8] <0.001
Substantial fatigue 218 [69.6] 503 [22] <0.001
Substantial fatigue, males 73 [56.2] -
Substantial fatigue, females 145 [79.2] -

The level of mental, physical, and total fatigue is presented as mean [SD], and the prevalence of substantial fatigue as n [%]. The Norwegian general population [NGP] compared to the results for patients with ulcerative colitis [UC] and Crohn’s disease [CD] are presented as the difference in means with 95% confidence interval [95% CI] for mental, physical, and total fatigue, and p-value for difference in prevalence of substantial fatigue.