Table 2.
Comparisons between recurrent cough and isolated chronic cough
| Characteristic | Recurrent cough (n = 222) | Isolated chronic cough (n = 265) | p-value |
|---|---|---|---|
| Age, years | 71.93 (71.31–72.55) | 72.82 (72.16–73.47) | 0.135 |
| Female gender, % | 58.6 | 71.3 | 0.003 |
| Body mass index, kg/m2 | 28.02 (27.40–28.64) | 27.26 (26.74–27.77) | 0.095 |
| Current smoking, % | 1.8 | 1.9 | 0.956 |
| Ever-smoking, % | 41.9 | 36.6 | 0.233 |
| Trigger sum | 3.7 (3.3–4.1) | 3.3 (2.94–3.67) | 0.212 |
| Family history of chronic cough, % | 42.3 | 34.7 | 0.085 |
| Allergy, % | 14.4 | 14.3 | 0.981 |
| Chronic obstructive pulmonary disease, % | 2.3 | 1.1 | 0.333 |
| Bronchiectasis, % | 1.4 | 1.5 | 0.884 |
| Current asthma, % | 18.0 | 13.3 | 0.148 |
| Chronic rhinosinusitis, % | 19.4 | 20.4 | 0.781 |
| Gastro-esophageal reflux disease, % | 27.7 | 27.1 | 0.878 |
| Obstructive sleep apnoea, % | 49.8 | 39.5 | 0.026 |
| Chronic sputum production, % | 46.4 | 39.4 | 0.123 |
| Analgesic intolerance, % | 11.9 | 7.7 | 0.122 |
| Symptom sum | 2.60 (2.32–2.88) | 2.63 (2.41–2.85) | 0.409 |
| Disorder sum | 1.89 (1.69–2.08) | 1.69 (1.53–1.85) | 0.187 |
| Depressive symptoms, % | 7.7 | 4.2 | 0.106 |
| Mean number of cough-related doctor`s visits during the past year | 0.58 (0.45–0.71) | 0.36 (0.19–0.53) | 0.007 |
| Subjects with ≥ 3 cough-related doctor`s visits during the past year, % | 6.0 | 3.8 | 0.272 |
| Symptoms of acute upper respiratory infection at onset of current cough, % | 33.7a | 10.7 | < 0.001 |
| Cough bout frequency (median, range) | 4–6 times per week (several times per day to ≤ 1 time per week)a | ≥ 1 time per day (several times per day to ≤ 1 time per week) | 0.847 |
| LCQ total score | 15.20 (14.64–15.76)a | 16.27 (15.98–16.55) | 0.001 |
| LCQ, physical score | 5.00 (4.83–5.18)a | 5.37 (5.29–5.46) | < 0.001 |
| LCQ, psychological score | 4.95 (4.76–5.15)a | 5.19 (5.07–5.30) | 0.032 |
| LCQ, social score | 5.24 (5.01–5.48)a | 5.70 (5.59–5.81) | < 0.001 |
p < 0.05 are highlighted in bold
The figures are presented as percentages or means and 95% confidence intervals unless stated otherwise
a among subjects with current cough (n = 90)