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. 2023 Nov 24;14:7692. doi: 10.1038/s41467-023-43538-y

Fig. 5. Effect of F10 and Mavacamten on haemodynamic parameters of Langendorff-perfused rat hearts.

Fig. 5

a Left ventricular systolic pressure (LVSP), b left ventricular end-diastolic pressure (LVEDP), c maximum and minimum rate of pressure development (dP dt−1max and dP dt-1min, respectively), d heart rate (HR) and e coronary flow (CF) in the absence of compounds (open circles) and in the presence of either 20 μmol L−1 F10 (left) or 1 μmol L-1 Mavacamten (right), and after washout. Data represent means ± s.e.m. with n = 4 rat hearts for F10 and n = 5 rat hearts for Mavacamten. Source data are provided as a Source Data file.