Table 4.
GEE Models
| Variable | Beta | 95% CI (Beta) | P | |
|---|---|---|---|---|
| GEE model 1: evolution of prolactin levels | Time (follow up vs baseline) | −34.163 | (−52.385; −15.942) | <.001 |
| Hit RT ISI SE | −0.95 | (−1.472; −0.428) | <.001 | |
| Letter and number test | −0.962 | (−1.58; −0.344) | .002 | |
| DDD of CPZ eq.* | 0.057 | (0.017; 0.097) | .005 | |
| PANSS negative* | −1.285 | (−2.468; −0.101) | .033 | |
| GEE model 2: evolution of oxytocin levels | Time (follow up vs baseline) | 0.303 | (−13.559; 14.164) | .966 |
| Sex (female vs male) | 33.391 | (9.683; 57.1) | .006 | |
| Hit RT ISI SE | −0.694 | (−1.376; −0.012) | .046 | |
| GEE model 3: evolution of homocysteine levels | Time (follow-up vs baseline) | −147.131 | (−437.621; 143.359) | .321 |
| Premorbid IQ | 21.907 | (2.576; 41.239) | .026 | |
| Hit RT BC SE | 24.844 | (1.956; 47.732) | .033 |
Abbreviations: DDD of CPZ eq., defined daily dose of chlorpromazine equivalent; GEE, Generalized Estimating Equation Models; Hit RT BC SE, standard error of hit reaction time by block; Hit RT ISI SE, standard error of hit reaction time by interstimulus interval; PANSS, Positive and Negative Syndrome Scale. *These variables were time dependent.