Table 4.
Ulcerative Colitis pre- and post-vedolizumab clinical, endoscopic, and laboratory values.
| Pre-Vedolizumab | Post-Vedolizumab | p | |
|---|---|---|---|
| UC Activity Index | 6.0 [2.3, 8.0] | 1.0 [0.0, 2.5] | <0.001 |
| CRP (mg/dL) | 3.2 [0.9, 11.3] | 2.5 [1.1, 6.7] | 0.777 |
| ESR (mm/h) | 11.0 [6.0, 27.0] | 7.5 [2.0, 16.8] | 0.245 |
| Fecal Calprotectin (μg/mg) | 1250.0 [299.0, 1250.0] | 196.0 [52.0, 2000.0] | 0.479 |
| Fecal Lactoferrin (μg/g) | 130.9 [50.9, 276.1] | 49.0 [28.2, 81.1] | 0.134 |
| UCEIS | 6.0 [3.0, 8.8] | 1.0 [0.0, 5.0] | <0.001 |
| BMI (kg/m2) | 24.4 [21.3, 28.7] | 25.87 [23.1, 29.9] | 0.337 |
| Vitamin D (ng/mL) | 33.2 [25.0, 38.8] | 45.0 [29.5, 60.0] | 0.008 |
| Albumin (g/dL) | 3.9 [3.0, 4.1] | 3.9 [3.6, 4.2] | 0.484 |
| Iron (umol/L) | 65.0 [34.0, 101.0] | 83.0 [52.3, 102.3] | 0.423 |
| TIBC (μg/dL) | 322.0 [283.5, 361.8] | 324.5 [295.0 353.0] | 0.563 |
| Ferritin (μg/L) | 54.5 [23.3, 135.0] | 55.0 [26.0, 122.0] | 0.766 |
| Iron Sat (%) | 27.0 [12.8, 29.0] | 25.5 [16.8, 32.3] | 0.477 |
| Vitamin B12 (pg/mL) | 619.0 [404.8, 840.8] | 548.0 [440.0, 687.0] | 0.637 |
| Folate (ng/mL) | 12.5 [10.7, 15.4] | 11.3 [9.2, 19.9] | 0.942 |
| Zinc (μg/dL) (mean (SD)) | 77.4 (19.6) | 79.9 (8.8) | 0.741 |
Statistically significant findings noted in bold.