Table 5.
Crohn’s Disease pre- and post-vedolizumab clinical, endoscopic, and laboratory values.
| Pre-Vedolizumab | Post-Vedolizumab | p | |
|---|---|---|---|
| Harvey–Bradshaw Index | 6.0 [3.0, 10.0] | 2.5 [1.0, 6.9] | 0.002 |
| CRP (mg/dL) | 3.4 [0.9, 13.5] | 2.7 [0.6, 6.7] | 0.44 |
| ESR (mm/h) | 16.5 [6.8, 46.3] | 6.0 [2.00, 19.8] | 0.004 |
| Fecal Calprotectin (μg/mg) | 326.5 [152.0, 495.7] | 80.5 [2.5, 235.3] | 0.234 |
| Fecal Lactoferrin (μg/g) | 98.9 [52.5, 175.7] | 30.0 [29.0, 96.2] | 0.735 |
| SES-CD | 15.0 [12.3, 23.3] | 3.0 [0.0, 8.5] | 0.002 |
| BMI (kg/m2) | 22.7 [19.7, 28.0] | 24.0 [21.6, 29.7] | 0.154 |
| Vitamin D (ng/mL) | 23.0 [17.0, 36.0] | 31.0 [24.0, 51.7] | 0.007 |
| Albumin (g/dL) | 3.3 [2.6, 4.2] | 3.5 [3.1, 4.1] | 0.658 |
| Iron (umol/L) | 41.0 [25.3, 75.8] | 82.5 [62.0, 107.3] | <0.001 |
| TIBC (μg/dL) | 297.0 [256.0, 330.5] | 312.0 [270.0, 344.3] | 0.305 |
| Ferritin (μg/L) | 74.0 [26.0, 141.0] | 117.0 [54.0, 273.5] | 0.064 |
| Iron Sat (%) | 15.0 [9.0, 25.0] | 27.0 [21.8, 36.3] | <0.001 |
| Vitamin B12 (pg/mL) | 545.0 [407.0, 969.0] | 572.0 [443.0, 946.3] | 0.55 |
| Folate (ng/mL) | 11.0 [6.8, 18.0] | 11.7 [8.9, 19.3] | 0.462 |
| Zinc (μg/dL) (mean (SD)) | 70.1 (18.5) | 74.3 (11.7) | 0.446 |
Statistically significant findings noted in bold.