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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Schematic representation of the importance played by the DipoleY and Q_VSA_PNEG descriptors to influence the compound (hTAAR1 and α2-ADR) binding affinity values. The two descriptors are endowed by the highest RI values in model (A,B), respectively. Compounds are represented as dots.