. 2023 Nov 2;11(11):1676. doi: 10.3390/vaccines11111676

Table 3.

COVID-19 case fatality rate (CFR) and Odds Ratio (OR) of death for adults with comorbidity vs. without, estimated by age group, before, during and after SARS-CoV-2 vaccination in Mexico (national data) during the sanitary emergency.

		Before Vaccination Wave 1–2		During Vaccination Wave 3		During Vaccination Wave 4		After Vaccination Wave 5–6		Entire Emergency
Age	Comorbidity	% CFR	OR (95% CI)	% CFR	OR (95% CI)	% CFR	OR (95% CI)	% CFR	OR (95% CI)	% CFR	OR (95% CI)
20–39	yes	2.94	4.59 (4.42–4.77) *	2.82	5.27 (5.02–5.52) *	0.50	8.4 (7.45–9.47) *	0.17	5.65 (4.65–6.87) *	1.87	6.06 (5.89–6.23) *
20–39	no	0.66	4.59 (4.42–4.77) *	0.55	5.27 (5.02–5.52) *	0.06	8.4 (7.45–9.47) *	0.03	5.65 (4.65–6.87) *	0.31	6.06 (5.89–6.23) *
40–59	yes	12.50	2.79 (2.75–2.83) *	9.19	3.68 (3.58–3.79) *	2.03	6.14 (5.78–6.52) *	0.42	5.08 (4.47–5.76) *	7.51	3.92 (3.86–3.97) *
40–59	no	4.87	2.79 (2.75–2.83) *	2.67	3.68 (3.58–3.79) *	0.34	6.14 (5.78–6.52) *	0.08	5.08 (4.47–5.76) *	2.03	3.92 (3.86–3.97) *
60–79	yes	34.75	1.73 (1.71–1.76) *	24.75	2.28 (2.22–2.35) *	12.11	3.20 (3.06–3.34) *	2.72	3.52 (3.25–3.81) *	24.04	2.44 (2.41–2.47) *
60–79	no	23.52	1.73 (1.71–1.76) *	12.59	2.28 (2.22–2.35) *	4.13	3.20 (3.06–3.34) *	0.79	3.52 (3.25–3.81) *	11.50	2.44 (2.41–2.47) *
80+	yes	51.13	1.38 (1.34–1.43) *	40.48	1.62 (1.53–1.72) *	31.79	1.75 (1.64–1.86) *	11.32	1.83 (1.68–2.00) *	38.85	1.70 (1.66–1.75) *
80+	no	43.06	1.38 (1.34–1.43) *	29.58	1.62 (1.53–1.72) *	21.08	1.75 (1.64–1.86) *	6.51	1.83 (1.68–2.00) *	27.17	1.70 (1.66–1.75) *
All adults	yes	17.82	4.07 (4.03–4.11) *	11.48	5.84 (5.74–5.94) *	4.40	8.44 (8.21–8.68) *	1.30	7.33 (6.97–7.71) *	11.01	5.94 (5.89–5.98) *
All adults	no	5.06	4.07 (4.03–4.11) *	2.17	5.84 (5.74–5.94) *	0.54	8.44 (8.21–8.68) *	0.18	7.33 (6.97–7.71) *	2.04	5.94 (5.89–5.98) *
All conditions		10.31	-	4.79	-	1.45	-	0.46	-	4.78	-

* With vs. without comorbidity had different CFR with p < 0.001.