Table 3.

Drug-loaded vesicular system currently in clinical trial.

Vesicular System	Payload	Phase of Study	Clinical Trial Identifier	Sponsor
Liposome	Irinotecan and Bevacizumab	I	NCT05854498	University of Wisconsin (Madison, WI, USA)
	Irinotecan-based FOLFIRI combined with Bevacizumab	II	NCT05969899	Fudan University (Shanghai, China)
	Fluorouracil and Irinotecan and Leucovorin	I, II	NCT03337087	Academic and Community Cancer Research United (Rochester, MN, USA)
Polymeric nanoparticle	Cetuximab	I	NCT03774680	Al-Azhar University (Cairo, Egypt)