Table 2.

Discrimination of PACVS from post-vaccination controls based on receptor antibodies and IL-6.

	ROC (AUC ± SE)	ROC (p)	Cut-off (U/mL) 1	Sensitivity (%) 2
AT1R	0.824 ± 0.027	<0.0001	≤10.7	89.7
ETAR	0.681 ± 0.035	<0.0001	≤11.5	64.9
M3R	0.741 ± 0.034	<0.0001	≤12.4	40.3
β2-adr-R	0.681 ± 0.036	<0.0001	≤11.6	66.5
α2b-adr-R	0.828 ± 0.025	<0.0001	≥25.2	90.3
M2R	0.703 ± 0.034	<0.0001	≥14.2	64.4
MASR	0.675 ± 0.037	<0.0001	≤44.0	72.3
IL-1-Rb	0.913 ± 0.019	<0.0001	≥5.8	66.5
IL-6	0.850 ± 0.022	<0.0001	≥2.3	82.0

¹ Derived from limits of 95% confidence intervals of post-vaccination controls, ² At 95 % specificity relative to post-vaccination controls.