Figure 4.
Evaluation of a direct effect of FF72 on CHIKV. Around 2.0 × 106 pfu/mL of CHIKV was incubated with vehicle or different concentrations of FF72 for 2 h at 37 °C prior to a plaque assay. The reduction in the amount of infective virions compared to the vehicle-treated control reflects the ability of FF72 extract to directly impair CHIKV to infect new cells. Statistical significance was calculated using a nonparametric Student t test, in which * represents p values lower than 0.05 compared to vehicle-treated condition.