Table 5.
Measles and rubella neutralizing-antibody responses.
| Uncoated HD-MAP n = 14 |
Low-Dose HD-MAP n = 16 |
High-Dose HD-MAP n = 16 |
MR-Vac n = 14 |
|
|---|---|---|---|---|
| Measles | ||||
| Day 0 | ||||
| GMT IU/mL (95% CI) |
0.673 (0.434–1.042) |
0.617 (0.264–1.447) |
0.949 (0.497–1.813) |
0.439 (0.221–0.873) |
| Day 7 | ||||
| GMT IU/mL (95% CI) |
0.705 (0.447–1.113) |
0.751 (0.323–1.742) |
1.284 (0.742–2.222) |
0.547 (0.337–0.889) |
| Seroconversion, No. (%) | 0 (0) | 0 (0) | 1 (6.3) | 2 (14.3) |
| Day 28 | ||||
| GMT IU/mL (95% CI) |
0.816 (0.55–1.209) |
1.811 (1.039–3.156) |
2.431 (1.603–3.687) |
1.456 (1.067–1.987) |
| Seroconversion, No. (%) | 0 (0) | 6 (37.5) | 3 (18.8) | 5 (35.7) |
| Day 56 | ||||
| GMT IU/mL (95% CI) |
0.768 (0.478–1.233) |
1.321 (0.702–2.484) |
1.595 (1.01–2.518) |
0.902 (0.623–1.306) |
| Seroconversion, No. (%) | 0 (0) | 3 (18.8) | 1 (6.3) | 3 (21.4) |
| Rubella | ||||
| Day 0 | ||||
| GMT IU/mL (95% CI) |
31.385 (17.875–55.104) |
24.609 (15.005–40.358) |
28.71 (20.697–39.826) |
27.137 (19.651–37.475) |
| Day 7 | ||||
| GMT IU/mL (95% CI) |
32.025 (18.762–54.662) |
26.214 (16.727–41.082) |
31.675 (22.149–45.298) |
23.527 (17.588–31.471) |
| Seroconversion, No. (%) | 0 (0) | 1 (6.3) | 0 (0) | 0 (0) |
| Day 28 | ||||
| GMT IU/mL (95% CI) |
33.164 (18.85–58.346) |
71.38 (50.062–101.774) |
92.385 (64.458–132.412) |
106.053 (56.96–197.458) |
| Seroconversion, No. (%) | 0 (0) | 6 (37.5) | 4 (25.0) | 5 (35.7) |
| Day 56 | ||||
| GMT IU/mL (95% CI) |
33.894 (19.073–60.233) |
70.821 (45.997–109.044) |
79.572 (58.992–107.329) |
74.518 (40.821–136.032) |
| Seroconversion, No. (%) | 0 (0) | 6 (37.5) | 3 (18.8) | 4 (28.6) |