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. 2023 Nov 9;15(11):646. doi: 10.3390/toxins15110646

Table 3.

Adverse health effect caused by AFB1 from UPP oil.

Low AFB1 Exposure (n = 84) High AFB1 Exposure (n = 84) p p Trend
Mean ± SD M (P25, P75) Mean ± SD M (P25, P75)
Age 49.48 ± 8.88 49.00 (43.00, 58.00) 48.74 ± 9.39 49.00 (42.00, 55.75) 0.732 0.057
Gender
male 30 (41.67%) 42 (58.33%) 0.062 0.035
female 54 (56.25%) 42 (43.75%)
BMI 23.32 ± 3.28 22.95 (20.93, 25.46) 23.29 ± 3.40 23.67 (20.52, 25.41) 0.876 0.048
AFB1 EDI (ng/kg BW/d) 0.62 ± 0.93 0.01 (0.00, 1.41) 17.95 ± 19.18 10.63 (6.28, 20.52) <0.001 -
AFT EDI (ng/kg BW/d) 1.09 ± 2.02 0.07 (0.02, 1.71) 21.84 ± 24.02 12.77 (7.89, 23.53) <0.001 <0.001
Liver function and lipid metabolism
AST (U/L) 22.63 ± 7.00 22.00 (18.00, 24.00) 23.77 ± 8.74 22.00 (18.00, 26.75) 0.761 0.920
ALT (U/L) 21.93 ± 14.76 14.76 (15.00, 24.00) 24.24 ± 17.59 18.00 (14.00, 27.75) 0.864 0.733
ALP (U) 82.70 ± 21.79 82.50 (70.25, 94.00) 86.18 ± 24.47 82.50 (68.00, 103.75) 0.569 0.895
GGT (U/L) 32.12 ± 25.82 23.00 (15.25, 37.00) 47.64 ± 51.87 30.00 (19.25, 53.50) 0.017 0.826
TP (g/L) 77.35 ± 3.59 77.30 (74.93, 79.80) 76.57 ± 3.91 77.00 (73.63, 79.15) 0.248 0.017
TBIL (μmol/L) 10.14 ± 5.19 8.90 (6.60, 12.10) 10.53 ± 4.49 10.05 (6.93, 12.50) 0.252 0.281
ALB (g/L) 47.73 ± 1.97 47.50 (46.33, 49.25) 47.78 ± 2.31 47.80 (46.23, 49.58) 0.706 0.576
CHOL (mmol/L) 5.09 ± 0.86 5.00 (4.58, 5.67) 4.94 ± 1.09 4.98 (4.24, 5.64) 0.549 0.170
HDL_CH (mmol/L) 1.44 ± 0.31 1.40 (1.20, 1.62) 1.49 ± 0.80 1.39 (1.09, 1.65) 0.465 0.482
LDL_CH (mmol/L) 3.14 ± 0.77 3.12 (2.64, 3.71) 2.98 ± 0.86 3.03 (2.22, 3.59) 0.201 0.059
TG (mmol/L) 1.51 ± 0.86 1.33 (0.90, 1.93) 1.88 ± 1.32 1.52 (1.04, 2.41) 0.105 0.583
Food consumption (g/kg bw/d)
Rice 5.62 ± 3.32 4.99 (3.11, 6.60) 5.89 ± 3.72 4.66 (3.43, 6.77) 0.860 <0.001
Rice Product 0.32 ± 0.50 0.16 (0.06, 0.39) 0.24 ± 0.31 0.15 (0.06, 0.27) 0.539 0.770
noodle 0.22 ± 0.29 0.14 (0.01, 0.32) 0.25 ± 0.31 0.16 (0.04, 0.31) 0.686 0.073
corn 0.15 ± 0.14 0.14 (0.03, 0.23) 0.17 ± 0.40 0.08 (0.00, 0.21) 0.135 0.550
bean 0.13 ± 0.16 0.06 (0.01, 0.17) 0.14 ± 0.15 0.09 (0.02, 0.22) 0.468 0.559
milk 0.21 ± 0.58 0.00 (0.00, 0.13) 0.37 ± 1.08 0.00 (0.00, 0.21) 0.530 0.191
peanut 0.16 ± 0.48 0.02 (0.00, 0.10) 0.12 ± 0.34 0.04 (0.00, 0.11) 0.810 0.493
nutCom 0.00 ± 0.01 0.00 (0.00, 0.00) 0.03 ± 0.11 0.00 (0.00, 0.00) 0.895 0.015
chill 0.02 ± 0.10 0.00 (0.00, 0.00) 0.05 ± 0.34 0.00 (0.00, 0.00) 0.191 <0.001
UPP oil 0.46 ± 0.60 0.31 (0.25, 0.44) 0.56 ± 0.68 0.34 (0.26, 0.55) 0.096 <0.001

Mann–Whitney test and linear regression test are used here. Bold character indicates p < 0.05.