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. 2023 Nov 9;15(11):646. doi: 10.3390/toxins15110646

Table 5.

Analysis of health effects caused by AFB1 from UPP oil in HBsAg- population.

Low AFB1 Exposure (n = 72) High AFB1 Exposure (n = 71) p
Mean ± SD M (P25, P75) mean ± SD M (P25, P75)
Age (year) 49.81 ± 8.92 49.00 (23, 58) 48.80 ± 9.39 50.00 (42.00, 56.00) 0.590
Gender
male 26 (36.11%) 32 (45.07%) 0.277
female 46 (63.89%) 39 (54.93%)
BMI 23.25 ± 3.30 23.03 (20.93, 25.24) 22.88 ± 3.15 23.59 (19.91, 25.28) 0.771
AFB1 EDI (ng/kg BW/d) 0.63 ± 0.94 0.01 (0.00, 1.41) 19.55 ± 20.38 12.57 (6.30, 23.30) <0.001
AFT EDI (ng/kg BW/d) 1.16 ± 2.14 0.04 (0.02, 1.76) 23.77 ± 25.58 15.34 (7.88, 29.72) <0.001
Liver function and lipid metabolism
AST (U/L) 22.35 ± 6.33 22.00 (18.00, 24.00) 22.32 ± 6.69 21.00 (17.00, 25.00) 0.936
ALT (U/L) 21.57 ± 14.48 18.50 (15.00, 23.75) 22.48 ± 16.82 18.00 (14.00, 23.00) 0.498
ALP (U) 83.49 ± 21.54 83.50 (71.00, 94.75) 85.35 ± 24.60 81.00 (68.00, 101.00) 0.913
GGT (U/L) 33.10 ± 26.22 23.50 (17.00, 40.25) 46.00 ± 53.98 28.00 (19.00, 48.00) 0.113
TP (g/L) 77.46 ± 3.78 77.55 (74.93, 80.10) 76.75 ± 3.95 77.10 (73.90, 79.20) 0.316
TBIL (μmol/L) 10.03 ± 4.84 8.90 (6.60, 12.00) 11.07 ± 4.54 10.60 (7.70, 13.10) 0.062
ALB (g/L) 47.83 ± 1.93 47.70 (46.43, 49.30) 48.12 ± 1.94 48 (46.70, 49.70) 0.341
CHOL (mmol/L) 5.16 ± 0.87 5.06 (4.62, 5.75) 4.94 ± 1.13 4.97 (4.25, 5.65) 0.336
HDL CH (mmol/L) 1.43 ± 0.32 1.40 (1.20, 1.64) 1.53 ± 0.85 1.46 (1.09, 1.73) 0.995
LDL CH (mmol/L) 3.20 ± 0.75 3.15 (2.71, 3.76) 2.98 ± 0.88 3.04 (2.21, 3.61) 0.134
TG (mmol/L) 1.56 ± 0.89 1.38 (0.90, 1.99) 1.82 ± 1.21 1.53 (1.05, 2.34) 0.273
Food consumption (g/kg bw/d)
Rice Product 0.32 ± 0.46 0.16 (0.07, 0.39) 0.24 ± 0.29 0.16 (0.08, 0.28) 0.639
noodle 0.21 ± 0.22 0.14 (0.01, 0.34) 0.26 ± 0.32 0.16 (0.04, 0.32) 0.475
corn 0.15 ± 0.13 0.15 (0.04, 0.24) 0.18 ± 0.43 0.08 (0.00, 0.22) 0.075
bean 0.13 ± 0.16 0.08 (0.01, 0.19) 0.14 ± 0.16 0.09 (0.01, 0.21) 0.720
milk 0.19 ± 0.60 0.00 (0.00, 0.05) 0.35 ± 1.00 0.00 (0.00, 0.21) 0.240
peanut 0.14 ± 0.43 0.02 (0.00, 0.11) 0.13 ± 0.36 0.04 (0.00, 0.12) 0.672
nutCom 0.00 ± 0.01 0.00 (0.00, 0.00) 0.03 ± 0.12 0.00 (0.00, 0.00) 0.988
chill 0.01 ± 0.04 0.00 (0.00, 0.00) 0.06 ± 0.37 0.00 (0.00, 0.00) 0.192
UPP oil 0.47 ± 0.63 0.31 (0.26, 0.44) 0.60 ± 0.73 0.34 (0.26, 0.60) 0.048
Liver function and lipid metabolism metric anomalies (abnormal %)
AST (abnormal %) 7 (9.72%) 6 (8.45%) 0.791
ALT (abnormal %) 4 (5.56%) 6 (8.45%) 0.726
ALP (abnormal %) 9 (12.50%) 9 (12.68%) 0.975
GGT (abnormal %) 18 (25.00%) 23 (32.39%) 0.328
TP (abnormal %) 2 (2.78%) 1 (1.41%) 1.000
TBIL (abnormal %) 2 (2.78%) 0 (0.00%) 0.497
ALB (abnormal %) 0 (0.00%) 0 (0.00%) -
CHOL (abnormal %) 33 (45.83%) 28 (11.27%) 0.439
HDL (abnormal %) 7 (9.72%) 12 (16.90%) 0.206
LDL (abnormal %) 27 (37.50%) 22 (30.99%) 0.412
TG (abnormal %) 25 (34.72%) 27 (38.03%) 0.681

Mann–Whitney test and Chi-square test are used here. Bold character indicates p < 0.05. “-” Indicates that there is a grid count of 0, and variance analysis cannot be performed.