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. 2023 Oct 24;15(11):2521. doi: 10.3390/pharmaceutics15112521

Table 6.

Ex vivo permeation studies of RS from control in situ gel and optimized glycethosomal in situ gel formulation (G5).

Permeation Parameter Optimized Glycethosomal Gel (G5) Control Gel
Jss (μg/cm2·h−1) 22.11 ± 3.37 4.07 ± 1.12
Kp × 10−3 (cm/h) 11.06 ± 1.75 2.04 ± 0.58
Er 5.43 -

Jss, drug flux at steady state; Kp, permeability coefficient; Er, enhancement ratio.