Table 6.
Ex vivo permeation studies of RS from control in situ gel and optimized glycethosomal in situ gel formulation (G5).
| Permeation Parameter | Optimized Glycethosomal Gel (G5) | Control Gel | 
|---|---|---|
| Jss (μg/cm2·h−1) | 22.11 ± 3.37 | 4.07 ± 1.12 | 
| Kp × 10−3 (cm/h) | 11.06 ± 1.75 | 2.04 ± 0.58 | 
| Er | 5.43 | - | 
Jss, drug flux at steady state; Kp, permeability coefficient; Er, enhancement ratio.