Table 3.
The effect of V. macrocarpon Aiton leaf extract and the corresponding extract loaded with arginine on some markers of lipid metabolism (mean ± SD, n = 6).
Indices | Experimental Groups | ||||||
---|---|---|---|---|---|---|---|
IC | IR | IR + PE | IR + PE + Arg | IR + Arg | IR + Arph | IR + Met | |
Blood serum | |||||||
TG, mmol/L | 1.45 ± 0.19 | 2.35 ± 0.24 a | 1.69 ± 0.15 b | 1.58 ± 0.18 b | 2.15 ± 0.21 c | 1.75 ± 0.47 | 1.63 ± 0.35 b |
TCh, mmol/L |
3.21 ± 0.19 | 6.99 ± 0.24 a | 4.09 ± 0.37 b | 3.57 ± 0.54 b | 5.44 ± 0.67 c | 4.95 ± 1.63 b | 3.38 ± 0.94 b |
Ch-LDL, µmol/mg protein | 2.33 ± 0.45 | 4.67 ± 0.87 a | 3.09 ± 0.68 b | 2.12 ± 0.45 b | 4.02 ± 0.63 | 3.82 ± 0.74 b | 2.57 ± 0.85 b |
Ch-HDL, µmol/mg protein | 0.99 ± 0.08 | 0.54 ± 0.11 a | 0.96 ± 0.10 b | 1.12 ± 0.13 b | 1.06 ± 0.19 b | 1.03 ± 0.12 b | 0.99 ± 0.08 b |
Liver homogenate | |||||||
PL, nmol/mg protein | 115.7 ± 11.3 | 82.9 ± 7.3 a | 93.6 ± 8.7 | 108.5 ± 9.4 b | 90.8 ± 8.5 | 90.4 ± 10.7 | 105.9 ± 8.4 b |
DG, nmol/mg protein | 14.23 ± 1.56 | 19.36 ± 1.75 a | 18.38 ± 2.11 | 16.54 ± 1.43 b | 17.28 ± 1.33 | 18.41 ± 0.96 | 15.81 ± 1.96 b |
Ch, nmol/mg protein | 10.26 ± 0.96 | 34.28 ± 4.59 a | 24.31 ± 1.94 | 15.94 ± 2.83 | 29.52 ± 4.59 c | 27.05 ± 3.81 c | 19.53 ± 1.79 b |
TG, nmol/mg protein | 57.34 ± 4.42 | 68.52 ± 5.17 a | 62.71 ± 4.25 | 58.47 ± 3.29 b | 67.41 ± 4.83 c | 5.91 ± 6.18 | 55.68 ± 3.93 b |
FFA, nmol/mg protein | 22.83 ± 1.45 | 35.33 ± 2.04 a | 29.45 ± 1.47 | 25.33 ± 0.94 b | 30.05 ± 1.23 c | 27.42 ± 1.11 b | 24.97 ± 1.73 b |
a—indicates a significant difference relative to the IC group (p ≤ 0.05). b—indicates a significant difference relative to the IR group (p ≤ 0.05). c—indicates a significant difference relative to IR + PE + Arg group (p ≤ 0.05).