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. 2023 Oct 31;15(11):635. doi: 10.3390/toxins15110635

Table 2.

Cinnamon oil synergy with organic acids on solid PDA.

Cinnamon Oil
1/2 MIC 1/4 MIC 1/8 MIC 1/16 MIC
Acetic Acid 1/2 MIC ++ ++ + +
1/4 MIC ++ + + +
1/8 MIC ++ + + +
1/16 MIC ++ + + +
Butyric Acid 1/2 MIC ++ ++ ++ +
1/4 MIC ++ + + +
1/8 MIC ++ + + +
1/16 MIC ++ + + +
Propionic Acid 1/2 MIC ++ ++ ++ +
1/4 MIC ++ + + +
1/8 MIC ++ + + +
1/16 MIC ++ + + +

Note: Each combination’s rating was based on its level of inhibition: “++” indicates complete inhibition; “+” indicates partial inhibition. The lowest concentration for a combination that received the “++” rating was designated its combined MIC. Dilutions were based on the full MICs of each compound: cinnamon (8000 µL/L air), acetic acid (1500 mg/kg), butyric acid (1760 mg/kg), propionic acid (2222 mg/kg).