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. 2023 Nov 9;10(11):648. doi: 10.3390/vetsci10110648

Table 1.

% viability of parasites determined colorimetrically via XTT method after 48 h incubation (106 promastigote/mL) and calculated IC50 (μg/mL) values (N.c: not calculated).

Compound Concentration (μg/mL)
1000 500 250 125 62.50 31.25 15.63 7.81 3.91 1.95 0.98 0.49 IC50
5a 72 78 100 100 100 100 100 100 100 100 100 100 N.c
5b 100 100 100 100 100 100 100 100 100 100 100 100 N.c
5c 100 100 100 100 100 100 100 100 100 100 100 100 N.c
5d 30 41 61 100 100 100 100 100 100 100 100 100 239.03
5e 82 100 100 100 100 100 100 100 100 100 100 100 N.c
5f 20 35 100 100 100 100 100 100 100 100 100 100 460.37
5g 100 100 100 100 100 100 100 100 100 100 100 100 N.c
5h 29 46 100 100 100 100 100 100 100 100 100 100 468.01
Drug Control
(Amphotericin B)
0 0 0 0 0 0 0 0 0 0 0 0 <0.49
Parasite Control 100 100 100 100 100 100 100 100 100 100 100 100 N.c