Table 1.
Comparison of the physicochemical characteristics of four different PEGs incorporated into the core of the cSLN matrix at varying quantities.
| PEG 1 | Quantity (mg) | PSD (nm) | PdI | ZP (mV) |
|---|---|---|---|---|
| Brij S100 | 50 | 348.8 | 0.252 | 23.4 |
| 150 | 243.3 | 0.118 | 23.7 | |
| 250 | 216.6 | 0.156 | 20.8 | |
| 350 | 166.2 2 | 0.177 | 23.0 | |
| Gelucire | 50 | 344.2 | 0.241 | 37.0 |
| 150 | 222.8 | 0.176 | 34.5 | |
| 250 | 226.7 | 0.159 | 38.9 | |
| 350 | 264.6 | 0.185 | 33.1 | |
| Myrj 52 | 50 | 326.4 | 0.203 | 31.9 |
| 150 | 223.7 | 0.129 | 32.3 | |
| 250 | 270.5 | 0.168 | 30.3 | |
| 350 | 246.8 | 0.153 | 28.9 | |
| Myrj S100 | 50 | 253.5 | 0.058 | 26.5 |
| 150 | 227.6 | 0.114 | 29.8 | |
| 250 | 222.8 | 0.051 | 28.0 | |
| 350 | 296.6 | 0.086 | 29.5 |
1 Polyethylene glycol (PEG), particle size distribution (PSD), polydispersity index (PdI), and zeta potential (ZP). 2 Bold: the smallest particle size of each quantity evaluated.