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. 2023 Nov 2;16(11):1554. doi: 10.3390/ph16111554

Figure 2.

Figure 2

Illustrative presentation of blood vessels and heart (a,B,c,D,e,F,g,H,i,J,k,L) in control rats (small italic letters) (a,c,e,g,i,k) and BPC 157-treated rats (capital italic letters) (B,D,F,H,J,L). Considerable failure or recovery was noted after decompression and reperfusion in rats who were subjected to the intra-abdominal hypertension of 25 mmHg for 60 min (a,B,c,D) (i), 30 mmHg for 30 min (e,F,g,H) (ii), or 40 mmHg for 30 min (iii) (i,J,k,L) and sacrificed after the corresponding reperfusion period (60 min (i) (a,B,c,D) or 30 min (ii (e,F,g,H); iii (i,J,k,L))) depending on whether they had received (sc) saline (controls) or BPC 157 at 3 min reperfusion times. Commonly, controls presented the marked congestion of the inferior caval vein (dashed violet arrows), a collapsed abdominal aorta (dashed red arrows), and a dilated heart. Contrarily, BPC 157-treated rats exhibited a consistent therapy effect and counteracted failed vessel and heart presentation; the inferior caval vein (full violet arrows) reversed to normal vessel presentation; the abdominal aorta (full red arrows) fully recovered and counteracted heart dilatation.