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. 2023 Nov 2;16(11):1554. doi: 10.3390/ph16111554

Figure 5.

Figure 5

Microscopic changes presented in the lung (a,B,c,D,e,F) in control rats (small italic letters) (a,b,e,f,i,j) and BPC 157-treated rats (capital italic letters) (B,D,F). Considerable lesions were noted after decompression and reperfusion in rats who were subjected to the intra-abdominal hypertension of 25 mmHg for 60 min (a,B) (i), 30 mmHg for 30 min (c,D) (ii), or 40 mmHg for 30 min (iii) (e,F) and sacrificed after the corresponding reperfusion period (60 min (i) (a,B) or 30 min (ii (c,D); iii (e,F)) depending on whether they had received (sc) saline (controls) or BPC 157 at 3 min reperfusion times. Commonly, control animals exhibited the marked congestion of the lung parenchyma, thickening of the alveolar membranes due to capillary congestion, pulmonary edema, and dilatation of larger blood vessels (a,c,e). No changes appeared in the BPC 157-treated rats (B,D,F). HE staining; magnification, 100×; scale bar, 200 μm.