Microscopic changes presented in the kidney (a,B,c,D,e,F) in control rats (small italic letters) (a,b,e,f,i,j) and BPC 157-treated rats (capital italic letters) (B,D,F). Considerable lesions were noted after decompression and reperfusion in rats who were subjected to the intra-abdominal hypertension of 25 mmHg for 60 min (a,B) (i), 30 mmHg for 30 min (c,D) (ii), or 40 mmHg for 30 min (iii) (e,F) and sacrificed after the corresponding reperfusion period (60 min (i) (a,B) or 30 min (ii (c,D); iii (e,F)) upon receiving (sc) saline (controls) or BPC 157 at 3 min reperfusion times. Commonly, control animals exhibited the marked congestion of the renal parenchyma with moderate vascular congestion, and interstitial edema occurred in control rats (a,c,e). No changes or mild congestion appeared in the BPC 157-treated rats (B,D,F). HE staining; magnification, 100×; scale bar, 200 μm.