Table 1.
AF and AF-adjusted prevalence of RSV among individuals in a study of the AF of RSV detection in mild and severe illness, Klerksdorp and Edendale, South Africa, June 2012 to May 2016.
| All enrolled participants | ||||||
|---|---|---|---|---|---|---|
| ILI |
SARI |
|||||
| Age group | Observed RSV detection rate n/N (%) |
AF % (95% CI) | AF-adjusted prevalence % |
Observed RSV detection rate n/N (%) |
AF, % (95% CI) | AF- adjusted prevalence % |
| <1 | 78/621 (13) | 84.9 (69.3-92.6) | 11 | 413/1328 (31) | 95.3 (91.1-97.5) | 30 |
| 1-4 | 116/1101 (11) | 74.6 (53.6-86.0) | 8 | 101/786 (13) | 83.4 (70.9-90.5) | 11 |
| 5-24 | 43/1531 (3) | 60.8 (21.4-80.5) | 2 | 6/287 (2) | 25.6 (0-73.8) | 1 |
| 25-44 | 49/1532 (3) | 64.1 (14.9-84.9) | 2 | 16/842 (1) | 26.1 (0-72.6) | <1 |
| 45-64 | 15/561 (3) | 69.6 (0-90.8) | 2 | 11/492 (2) | 52.6 (0-87.9) | 1 |
| 65+ | 2/103 (2) | 48.0 (0-94.7) | 1 | 6/177 (3) | 80.6 (0-96.8) | 2 |
| Individuals living with HIV | ||||||
| Observed RSV detection rate | ILI | Observed RSV detection rate | SARI | |||
| AF, % (95% CI) | AF-adjusted prevalence, % |
AF, % (95% CI) | AF-adjusted prevalence, % |
|||
| <1 | 0/8 (0) | 0 (0-92.5) | ND | 3/20 (15) | 0 (0-71.9) | ND |
| 1-4 | 1/19 (5) | 75.8 (0-96.5) | 4 | 9/91 (10) | 72.1 (0-95.9) | 7 |
| 5-24 | 12/230 (5) | 78.1 (36.5-92.5) | 4 | 5/114 (3) | 55.4 (0-87.7) | 3 |
| 25-44 | 29/865 (3) | 76.6 (13.6-93.7) | 2 | 16/722 (2) | 61.8 (0-90.0) | 1 |
| 45-64 | 6/227 (3) | 75.7 (0-96.1) | 2 | 8/299 (3) | 80.4 (0-97.6) | 2 |
| 65+ | 0/10 (0) | No RSV | NA | 3/33 (9) | 87.4 (0-99.4) | 8 |
| HIV-uninfected individuals | ||||||
| ILI | SARI | |||||
| Observed RSV detection rate | AF, % (95% CI) | AF-adjusted prevalence, % |
Observed RSV detection rate | AF, % (95% CI) | AF-adjusted prevalence, % |
|
| <1 | 68/574 (12) | 87.5 (72.2-94.4) | 11 | 371/1109 (33) | 96.7 (93.0-98.5) | 32 |
| 1-4 | 112/1038 (11) | 77.7 (56.6-88.5) | 9 | 91/656 (14) | 84.6 (70.3-92.0) | 12 |
| 5-24 | 27/1158 (2) | 39.0 (0-74.1) | 1 | 1/123 (1) | 0 (0-78.7) | ND |
| 25-44 | 18/588 (3) | 30.9 (0-76.0) | 1 | 0/93 (0) | 0(0-53.5) | ND |
| 45-64 | 7/301 (2) | 60.8 (0-91.0) | 1 | 0/162 (0) | 0 (0-91.3) | ND |
| 65+ | 1/84 (1) | 46.0 (0-94.5) | 0.5 | 3/129 (2) | 64.3 (0-94.8) | 1 |
AF, Attributable fraction; CI, confidence interval; ILI, influenza-like illness; ND, not determined; RSV, respiratory syncytial virus; SARI, severe acute respiratory illness.