Table 2.
The association between BMI trend and variation in late-middle age and risk of dementia in older age
| Variables | Types | Model 1 | Model 2 | Model 3 | Model 4 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No.participants | No.event | RR (95% CI) | P value | No.participants | No.event | ARR (95% CI) | P value | No.participants | No.event | ARR (95% CI) | P value | No.participants | No.event | ARR (95% CI) | P value | ||
| BMI trend | Ascend | 6693 | 489 | Reference | < 0.001 | 6672 | 486 | Reference | 0.002 | 6643 | 482 | Reference | 0.002 | 6643 | 482 | Reference | 0.001 |
| Decline | 4154 | 411 | 1.35 (1.19–1.54) | 4141 | 409 | 1.23 (1.08–1.4) | 4125 | 407 | 1.24 (1.08–1.42) | 4125 | 407 | 1.27 (1.11–1.46) | |||||
| BMI variation | Low | 6622 | 490 | Reference | < 0.001 | 6601 | 486 | Reference | < 0.001 | 6576 | 481 | Reference | < 0.001 | 6576 | 481 | Reference | < 0.001 |
| High | 4225 | 410 | 1.31 (1.15–1.5) | 4212 | 409 | 1.39 (1.22–1.6) | 4192 | 408 | 1.37 (1.19–1.56) | 4192 | 408 | 1.36 (1.19–1.56) | |||||
BMI Body mass index
Model 1 was a univariate model for the BMI trend
Model 2 was additionally adjusted for sex, education level, ethnicity, year of aged 65, and marital status
Model 3 was additionally adjusted for smoking status, alcohol consumption, and longstanding illness status
Model 4 was additionally adjusted for the mean BMI group