Table 3.

Subgroup-analysis of association between higher Oxidative balance score and risk of cancer

Higher oxidative balance score and odds of cancer in case-controls	Subgroups	Number of arms	OR (95% CI)	MODEL	Heterogeneity assessment
					I2%	Q test	P-value
Gender	Both	8	0.64 (0.53.0.76)	Random	90.1	70.40	< 001
	Female	2	0.71 (0.56, 0.89)		15.10	1.18	0.278
Cancer type	Colorectal	7	0.66 (0.57.0.81)	Random	91.2	55.91	< 001
	Breast	2	0.71 (0.57, 0.89)		15.1	1.18	0.278
Higher oxidative balance score and risk of cancer in cohorts	Sub-group	Number of arms	HR (95% CI)	MODEL	Heterogeneity assessment
					I2%	Q test	P-value
Stage of cancer	Typical case	6	0.86 ( 0.67,1.05)	Random	88.5	52.34	< 001
	Non-advance	3	1.05 (0.96, 1.14)		25.7	21.03	0.260
	Advance, stage 3,4	3	1.14 (0.97, 1.34)		0.0	1.12	0.640
Cancer type	prostate	3	1.15 (1.05,1.26)	Random	0.0	0.79	0.674
	colorectal	2	0.62 (0.54,0.71)		0.0	0.69	0.408
Gender	Male	4	1.05 (0.95,1.16)	Random	69.6	29.63	0.001
	Female	3	0.74 (0.58,1.06)		82.4	11.38	0.003