Fig. 3.

Diagram illustrating the intercellular communication network among NPCs exhibiting varying AA metabolic activity and other co-localized cell types. A, B Diagram depicting interactions between NPCs of varying AA metabolic activity and other cell types. The thickness of the connecting lines between two cell types indicates their interaction weight or intensity. C Point plots of outgoing and incoming signal pathways in various cell types. D Heatmap depicting the intensity of intercellular interactions among eight distinct cell type© (E). Summary of LR interactions between NPCs of varying AA metabolic activity and other cell types. The horizontal axis represents ligand cells and their corresponding receptor cells, while the vertical axis represents different signaling pairs