Table 2.
Relations between HOMA index with demographic, clinical and paraclinical characteristics of participants (n = 160)
| Parameter (quantitative) | HOMA | ||
| Correlation coefficient (r) | P – value (Spearman’s test) | ||
| Age (years) | −0.026 | 0.744 | |
| Height(cm) | −0.007 | 0.935 | |
| Weight(kg) | − 0.078 | 0.328 | |
| age at menarche (years) | 0.048 | 0.551 | |
| FSH1 (IU/l) | 0.028 | 0.721 | |
| LH2 (IU/l) | −0.174 | 0.027 | |
| MDA3 (μM) | 0.119 | 0.135 | |
| Hb4 (g/dl) | 0.244 | 0.002 | |
| TSH5 (mU/l) | --0.052 | 0.511 | |
| T46 (nmol/l) | −0.041 | 0.610 | |
| PLT7 (N/mm3) | 0.100 | 0.208 | |
| BMI8 (kg/m2) | −0.008 | 0.316 | |
| SHBG9 (nmol/l) | −0.151 | 0.061 | |
| FAI10 | 0.178 | 0.024 | |
| WHR11 | 0.053 | 0.506 | |
| Parameter (Qualitative) | Grouping |
HOMA-IR (Median ± IQR) |
P – value |
| Education | Illiterate (n:5) | 6.03 ± 1.98 | 0.16** |
| Under diploma/ Diploma (n:62) | 3.61 ± 3.61 | ||
| college education (n:93) | 3.85 ± 3.18 | ||
| Number of ovarian cysts | < 2 (n:7) | 3.65 ± 3.14 | 0.55* |
| > = 2 (n:153) | 3.89 ± 3.29 | ||
| Job | Housewife (n:57) | 6.76 ± 2.88 | 0.13* |
| Employed (n:103) | 3.74 ± 3.31 | ||
| Phenotype group | Classic (A&B) (n:120) | 4.64 ± 3.16 | 0.001* |
| Non classic (C&D) (n:40) | 2.58 ± 3.65 | ||
| PCOS phenotype△ | A (n:83) | 3.57 ± 3.18 | < 0.001** |
| B (n:37) | 5.73 ± 1.55 | ||
| C (n:21) | 2.61 ± 3.80 | ||
| D (n:19) | 2.56 ± 3.71 | ||
| Marital status | Single (n:96) | 3.83 ± 3.40 | 0.31* |
| Married (n:64) | 3.90 ± 3.17 | ||
| Physical activity | No (< 90 minutes per week) (n:66) | 4.96 ± 3.03 | 0.03* |
| Yes (> = 90 minutes per week) (n:94) | 3.46 ± 3.37 | ||
| Economic group | poor (expenditure more than income) (n:44) | 3.92 ± 2.91 | 0.07* |
| Good (expenditure less than income) (n:116) | 3.81 ± 2.68 | ||
| BMI group (kg/m2) | Normal (< 25) (n:85) | 3.94 ± 3.39 | 0.25* |
| Overweight/obese (> = 25) (n:75) | 3.63 ± 3.08 | ||
1. Follicle stimulating hormone, 2. Luteinizing hormone, 3. Malonaldehyde, 4. Hemoglobin, 5. Thyroid stimulating hormone, 6. Thyroxin, 7. Platelets, 8. Body mass index, 9. Sex hormone binding globulin, 10. Free androgen index, 11. Waist-to-hip ratio
△ Significance values have been adjusted with pairwise comparisons by the Bonferroni correction for multiple tests. Significant results were: Phenotypes A & b: P – value > 0.001, phenotypes C & B: P – value > 0.001, phenotypes D & B: P – value > 0.001
* Mann-Whitney U Test, ** Kruskal-Wallis