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. 2023 Nov 24;27:121. doi: 10.1186/s40824-023-00461-z

Fig. 12.

Fig. 12

CINMs-based PTT for bone tissue regeneration. A Schematic diagram of synthetic and therapeutic mechanisms of CuS@BSA/rGO-PDA for synergistic antibacterial and osseointegration. B X-ray examination of intrafemoral implants in rats. C Micro-CT scanning of 3D reconstruction of new bone tissues around the implant and no-implant groups at 8 weeks. TNT represents TiO2 nanotubes. D HE and Masson staining of rat femurs after different treatments. E Macroscopic observation of knee-joints after implantation and images of Mueller-Hinton Broth medium and colony plates from different treated posterior rods. Reproduced with permission [224]. Copyright 2021, Elsevier