Table 3.
Effects of O. rochetiana on Gastrointestinal Transit in Castor Oil-Induced Diarrhea
| Groups | MSIL (cm) | MDTCM (cm) | PI (%) | % Inhibition |
|---|---|---|---|---|
| DW10 | 52.2±0.60 | 51.33±0.74 | 86±0.13 | _ |
| Lop3 | 54.7±0.08 | 24.4±0.2a***b**c*d* | 43±0.49a**b**c* | 60.67 |
| MEOR100 | 52.3±0.15 | 49.23±0.6a** | 82±0.71a* | 15.46 |
| MEOR200 | 54.8±1.20 | 41.8±0.3a***b** | 65±0.77a**b** | 23.00 |
| MEOR400 | 53.0±0.40 | 31.5±0.26a***b***c** | 46.28±0.44a***b***c** | 49.17 |
Notes: All values are expressed as the mean ± standard error of the mean (SEM) (n = 6). Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test; a, compared to DW10; b, compared to MEOR100; c, compared to MEOR200; d, compared to MEOR400; *p<0.05, **p<0.01, ***p<0.001.
Abbreviations: DW10, distilled water 10 mg/kg; Lop3, loperamide 3 mg/kg; MEOR, methanol extract of O. rochetiana; MDTCM, mean distance traveled by charcoal meal; MSIL, mean small intestine length; PI, peristaltic index.