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Representative cases showing coregistered cortical map on BBB permeability map in patient of amyloid (18F-florbetaben) PET positive. The volumes of interest of the whole cortex from T1-weighted volumetric images (upper line) were coregistered to the BBB permeability map (lower line) to avoid overlap of brain mask and cerebrospinal spaces and to extract the Ktrans values using a mutual information-based algorithm.
