Mean arterial pressure (Left) and heart rate (Right) in 1.8-kg piglets (a, b), 4-kg-piglets (c, d), and 15-kg piglets (e, f) during the 4-hour cooling period. Brackets show range of times when values differed significantly from baseline by one-way repeated measures ANOVA and the Dunnett’s test for multiple comparison to baseline. Values are means ± SD.