Table 1..

Average (Avg.) and standard deviation (SD) values of inflammatory biomarkers in plasma and stool for ALS patients as well as for partner/caregiver controls, and the average and standard deviation of the difference between patient and control.

Group		ALS patients (n = 10)		Partner/caregivers (n = 10)		Δ (n = 10)		p Value*	Adjusted p value**
Medium	Analytea	Avg.	SD	Avg.	SD	Avg.	SD
Plasma	CRP (x10−6)	1.73	1.67	3.25	2.83	−1.52	3.19	0.17	0.46
	IFN-γ	3.94	1.63	7.14	5.26	−3.19	6.33	0.15	0.46
	IL-10	0.35	0.12	0.47	0.44	−0.12	0.43	0.41	0.60
	IL-1β	0.05	0.05	0.06	0.12	−0.01	0.10	0.73	0.79
	IL-12p70	0.16	0.17	0.23	0.20	−0.07	0.27	0.44	0.61
	IL-13	0.76	0.68	0.58	0.41	0.19	0.85	0.50	0.66
	IL-2	0.26	0.12	0.39	0.14	−0.13	0.21	0.08	0.38
	IL-4	0.03	0.01	0.03	0.01	0.01	0.01	0.19	0.46
	IL-6	0.71	0.43	0.78	0.73	−0.07	0.87	0.81	0.81
	IL-8	2.25	0.79	3.05	2.12	−0.80	1.98	0.23	0.46
	LBP	3125	893	3684	1469	−558	1819	0.36	0.56
	LPS	6.01	0.72	6.10	1.08	−0.09	1.04	0.79	0.81
	TNF	3.19	0.46	3.40	1.41	−0.20	1.35	0.65	0.77
Stool	CRP (x10-6)	449	651	1093	1296	−644	1610	0.24	0.46
	IFN-γ	29.7	58.6	55	111.12	−25.32	133.6	0.56	0.70
	IL-10	0.20	0.16	0.64	0.63	−0.45	0.57	0.03	0.38
	IL-1β	39.0	34.0	90.5	92.7	−51.5	93.9	0.12	0.43
	IL-12p70	0.95	0.70	1.14	1.18	−0.19	1.42	0.68	0.77
	IL-13	11.39	19.98	23.09	31.63	−11.9	37.0	0.34	0.56
	IL-2	26.2	56.9	65.4	82.3	−39.2	109	0.28	0.50
	IL-4	0.16	0.10	0.23	0.14	−0.06	0.09	0.06	0.38
	IL-6	0.25	0.23	0.52	0.54	−0.26	0.44	0.09	0.38
	IL-8	179	226	806	934	−627	902	0.06	0.38
	LBP	0.42	0.50	2.92	6.09	−2.49	6.21	0.24	0.46
	TNF	1.29	0.88	2.89	3.03	−1.61	2.58	0.08	0.38

p Values were calculated by paired t-test.

^aUnits are pg/ml except for LPS, which is EU/ml.

^*p Value for paired t-test.

^**p Value adjusted for multiple comparisons using Benjamini–Hochberg correction.