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. 2023 Nov 25;14(11):768. doi: 10.1038/s41419-023-06234-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Mice were treated with IMQ and sulforaphane daily for 7 consecutive days and sacrificed on day 8. n = 5. b The macroscopic appearance and H&E staining (magnification × 100) of the skin tissue. c The PASI scores of the skin tissue. d Spleen weight index, which was measured by taking spleen weight to body weight. e The average epidermal thickness (μM), derived from 18–20 random measurements. Statistical significance was determined by one-way ANOVA analysis. *p < 0.05, **p < 0.01 and ***p < 0.001.