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. 2023 Nov 25;14(11):768. doi: 10.1038/s41419-023-06234-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Chemical structure of SFN. b PPI network of SFN targets predicted by SuperPred(https://prediction.charite.de/) and OMIM (https://www.omim.org/). The yellow nodes represent the large hub nodes, and the blue nodes represent the other nodes. The node size is proportional to the target degree in the network. c Target genes were retrieved by taking the intersection of targets of SFN and genes related to psoriasis, and the PPI network of the target genes (d) was constructed by the STRING database. e Interrelation analysis of pathways via assessment of Reactome processes in ClueGO.