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Pennyroyal loaded NLCs blocking clonogenicity in MCF-7 cancerous breast cells. pennyroyal-NLCs, free pennyroyal, and pennyroyal-NLCs/MTX reduced the formation of breast cancerous cell colonies. The data indicate mean ± SD (n = 3); ****P < 0.0001, versus multiple comparisons. NLCs: nanostructured lipid carriers, MTX: methotrexate, and SD: standard deviation
