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. 2023 Jan 23;13(4):688–700. doi: 10.34172/apb.2023.071

Table 4. Allosteric inhibitors of GSK-3β in AD .

Drug Structure Class Mode of action References
Palinurin

graphic file with name apb-13-688-g019.jpg

 Furanosesquiterpenes Allosteric GSK-3β inhibition 51
Manzamine A

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 Manzamines GSK-3 allosteric modulator 68
VP0.7

graphic file with name apb-13-688-g021.jpg

 Quinoline derivative Non-ATP GSK-3β competitive inhibition 69
Benzothiazinones (BTO-5h)

graphic file with name apb-13-688-g022.jpg

 Benzothiazinones GSK-3β allosteric inhibition 21