Table 4.
Therapeutic Goals for Modifiable Cardiovascular Risk Factors
| Risk Factor | Target | Notes |
|---|---|---|
| Systolic blood pressure | ||
| 18–65 years | 130 mmHg | Standard target |
| >65 years | 130–139 mmHg | If tolerated |
| Diastolic blood pressure | 70–79 mmHg | |
| LDL-C targeta | ||
| <100 mg/dL | Patients with moderate CV risk or young patients with diabetes mellitus duration <10 years without other risk factors | |
| <70 mg/dL | Patients with high CV risk or diabetes mellitus without target organ damage | |
| <55 mg/dL | Patients with very high CV risk or diabetes mellitus with target organ damage or severe CKD or established atherosclerotic CVD | |
| Triglycerides | <150 mg/dL | |
| Fasting glycemia | <110 mg/dL | |
| HbA1c | <6.5% |
Notes: aIn patients with high and very high CV risk, at least a 50% reduction is required.
Abbreviations: CKD, chronic kidney disease; CV, cardiovascular; CVD, cardiovascular disease; HbA1c, glycated hemoglobin; LDL-C, low-density lipoprotein cholesterol.