Table 1.

Summary of the observed changes in t_lag, t_1/2, size of WT α-syn, A30P, and A53T fibrils, the amount of parallel β-sheet and toxicity of these protein aggregates according to LDH assay

	WT				A30P				A53T
	POPS	DOPS	DMPS	DSPS	POPS	DOPS	DMPS	DSPS	POPS	DOPS	DMPS	DSPS
tlag	↓	↓	↓	↓	x	↓	↓	↓	↑	↑	↑	↑
t1/2	↓	x	x	x	↓	x	↓	x	↑	↑	x	x
Size
Parallel β-sheet	x	x	x	x	x	↓	↓	↓	x	x	x	↑
Toxicity	↑	↓	x	↓	x	↑	↑	↑	↓	↓	↓	x

α-syn, α-synuclein; DMPS, 1,2-dimyristoyl-sn-glycero-3-phospho-Lserine; DOPS, 1,2-dioleoyl-sn-glycero-3-phospho-L-serine; DSPS, 1,2-distearyl-sn-glycero-3-phospho-L-serine; LDH, lactate dehydrogenase; POPS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine.