Table 2.
Incidence rates and hazard ratios for hypertension and type 2 diabetes in women with and without a history of preterm delivery
Outcome | Hypertension | Type 2 diabetes mellitus | ||
Preterm delivery | Term delivery | Preterm delivery | Term delivery | |
Population, n | 3247 | 12 154 | 3274 | 12 327 |
Events, n (%) | 73 (2.2) | 194 (1.6) | 35 (1.1) | 79 (0.6) |
Person-years | 20 124 | 74 653 | 20 565 | 76 735 |
Follow-up, median (IQR), y | 5.44 (2.28–9.27) | 5.01 (2.13–9.62) | 5.50 (2.33–9.43) | 5.10 (2.16–9.74) |
Crude incidence rate per 10 000 person-years | 36 | 25 | 17 | 10 |
Crude HR (95%CI, p value) | 1.42 (1.09 to 1.86, 0.011) | 1.67 (1.12 to 2.48, 0.012) | ||
Adjusted HR (95%CI, p value) | Model 1* | 1.30 (0.99 to 1.70, 0.060) | 1.35 (0.90 to 2.02, 0.144) | |
Model 2† | 1.18 (0.90 to 1.56, 0.236) | 1.10 (0.72 to 1.68, 0.670) |
*Model 1: adjusted for age, ethnicity, BMI, smoking status.
†Model 2: adjusted for model 1 variables plus lipid-lowering medication prescription, cardiovascular disease, migraine, sexually transmitted diseases, polycystic ovarian syndrome, chronic inflammatory diseases, reproductive tumour, hypertension for T2DM outcome, and T2DM for hypertension outcome.
BMI, Body Mass Index; T2DM, type 2 diabetes mellitus.