TABLE 2.

New antigens added to pre-existing blood group systems by the Working Party: Reported at the business meeting in Basel in June 2019, the second virtual business meeting in December 2020 and the third virtual business meeting in June 2021

Business meeting	ISBT number	Blood group system	Antigen number	Alt. name	Antigen prevalence	Allele name	Molecular basis	Protein change	SNV (rs-number)	GenBank	Reference
Second virtual	ISBT 002	MNS	MNS50	SUMI	Low	GYPA*50	GYPA c.91A>C	GPA p.Thr31Pro	Pending	LC495310	[25]
Third virtual	ISBT 004	RH	RH63	CETW	Low	To be determined	RHCE c.486C>G	RhCE p.Asn162Lys	rs199725473	MZ326705	Manuscript in preparation
Basel	ISBT 005	LU	LU28	LUNU	High	LU*02.-28	BCAM c.121G>A	BCAM p.Val41Met	rs957795435	MK965667	[26]
Basel	ISBT 005	LU	LU29	LURA	High	LU*02.-29	BCAM c.1351A>C	BCAM p.Lys451Gln	rs28399630	Pending	[27]
Third virtual	ISBT 010	DI	DI23	DIST	Low	DI*02.23	SLC4A1 c.1447G>A	CD233 p.Gly483Ser	rs544557335	Pending	[28]
Second virtual	ISBT 013	SC	SC8	SCAR	High	SC*01.-08	ERMAP c.424C>G	ERMAP p.Gln142Glu	Pending	MK933825	[29]
Second virtual	ISBT 013	SC	SC9	SCAC	High	SC*01.-09	ERMAP c.217C>T, c.219C>T	ERMAP p.Arg73Cys p.Arg73Cys	rs149787850 rs33954154	MW427218	[31]
Second virtual	ISBT 020	GE	GE12	GECT	High	GE*01.-13	GYPC c.59C>T	GPC p.Pro20Leu	rs143216051	Pending	[32]
Second virtual	ISBT 020	GE	GE13	GEAR	High	GE*01.-14	GYPC c.118G>A c.333A>C	GPC p.Gly40Arg p.Gly111Gly	rs772372126 rs1050967	Pending	[33]
Basel	ISBT 022	KN	KN10	KDAS	Average	KN*01.10	CR1 c.4843A>G	CR1 p.Ile1615Val	rs6691117	Pending	[35]
Second virtual	ISBT 022	KN	KN11	DACY	Average	KN*01	CR1 c.3623A	CR1 p.His1208	rs2274567	Pending	[36]
Second virtual	ISBT 022	KN	KN12	YCAD	Average	KN*01.12	CR1 c.3623A>G	CR1 p.His1208Arg	rs 2274567	Pending	[36]
Basel	ISBT 026	JMH	JMH7	JMHN	High	JMH*01.-07	SEMA7A c.709G>A c.1545A>G c.1865G>A	CD108 p.Asp237Asn p.Gln515Gln p.Arg622His	rs140707085 rs741761 rs140128092	Pending	[37]
Second virtual	ISBT 026	JMH	JMH8	JMHA	High	JMH*01.-08	SEMA7A c.507C>T c.556G>A c.1545A>G	CD108 p.Tyr169Tyr p.Glu186Lys p.Gln515Gln	rs2075589 rs572867366 rs741761	MT017654	[39]
Second virtual	ISBT 030	RHAG	RHAG5	Kg	Low	RHAG*01.-03	RHAG c.490A>C	RhAG p.Lys164Gln	rs144305805	LC508243	[41]

Abbreviations: GPA, glycophorin A; GPC, glycophorin C; SNV, single nucleotide variant.