Figure 1:

Schematic of components of the integrated global model

Abbreviations: cVDPV, circulating VDPV; DEB, differential equation-based model; DES, discrete-event simulation model; iVDPV, immunodeficiency-associated vaccine-derived poliovirus; IPV, inactivated poliovirus vaccine; OPV, oral poliovirus vaccine; oSIAs, outbreak supplemental immunization activities; PAVD, polio antiviral drug; pSIAs, preventive supplemental immunization activity; VAPP, vaccine-associated paralytic polio; VDPV, vaccine-derived poliovirus; WPV, wild poliovirus