Table 2:
Expected value of iVDPV-related introductions (median) [range] | ||||
---|---|---|---|---|
Scenario | iVDPV1 | iVDPV2 | iVDPV3 | Total |
No PAVD base case | 22 (21) [9 – 46] | 21 (21) [2 – 53] | 10 (10) [1 – 22] | 53 (53) [28 – 81] |
Passive PAVD, 40% effectiveness | 22 (21) [9 – 46] | 21 (20) [1 – 53] | 10 (10) [1 – 22] | 53 (52) [28 – 80] |
Active PAVD, 90% effectiveness | 14 (13) [5 – 31] | 7 (6) [0 – 17] | 10 (9) [1 – 22] | 30 (29) [15 – 52] |
Abbreviations:iVDPV(1,2,3), immunodeficiency-associated vaccine-derived poliovirus (type 1, 2, 3); PAVD, polio antiviral drug