Table 3.

Logistic-Regression Analyses for Death at 28 Days.

Variable	No. of Patients in Analysis*		Odds Ratio (95% confidence interval)†
		For Each Variable	Remdesivir vs. ZMapp	MAb114 vs. ZMapp	REGN-EB3 vs. ZMapp
Duration of symptoms	615	1.11 (1.05–1.16) per day of symptoms‡	1.04 (0.66–1.64)	0.49 (0.31–0.78)	0.45 (0.28–0.73)
Nucleoprotein Ct value	620	0.66 (0.62–0.71) per 1 unit increase	1.29 (0.71–2.34)	0.39 (0.21–0.73)	0.37 (0.20–0.68)
Years of age	623	1.00 (1.00–1.01) per 1 yr increase	1.07 (0.68–1.66)	0.52 (0.33–0.82)	0.48 (0.31–0.77)
Creatinine level§	507	1.43 (1.31–1.56) per 1 mg/dl increase	0.93 (0.54–1.59)	0.48 (0.27–0.84)	0.38 (0.21–0.67)
AST level§	380	1.15 (1.11–1.20) per 100 U/liter increase	1.06 (0.54–2.05)	0.31 (0.14–0.67)	0.29 (0.14–0.63)
ALT level§	511	1.43 (1.33–1.54) per 100 U/liter increase	0.95 (0.54–1.68)	0.37 (0.20–0.69)	0.36 (0.20–0.66)
Patient-reported vaccination§	620	0.37 (0.24–0.55) yes vs. no	1.06 (0.67–1.68)	0.48 (0.30–0.77)	0.44 (0.28–0.71)

^*Model estimates include data from patients who were enrolled after the REGN-EB3 group was added. The number of patients in the analysis reflects the number enrolled after the REGN-EB3 group was added for whom data were available for each variable.

^†Each row shows the odds ratios derived from a multivariate logistic-regression model that included the variable listed plus the four treatment groups.

^‡The variable reflects each additional day of symptoms before admission to the treatment center.

^§Because of its clinical significance, the variable was added after the statistical analysis plan was finalized but before analysis of the data.