Table 1.

Trial registration data set

Data category	Information
Primary registry and trial identifying number	International Clinical Trials Registry Platform NL9793
Date of registration in primary registry	14 October, 2021
Secondary identifying numbers	NL78840.029.21
Source(s) of monetary or material support	Amsterdam UMC, location VUmc, department of Rehabilitation
Primary sponsor	Amsterdam UMC, location VUmc, department of Rehabilitation
Secondary sponsor(s)	Amsterdam Movement Sciences Institute
Contact for public queries	MdL, m.e.deleeuwerk@amsteramumc.nl
Contact for scientific queries	MdL, m.e.deleeuwerk@amsteramumc.nl Amsterdam UMC, location VUmc, department of Rehabilitation, Amsterdam, The Netherlands
Public title	Optimal Physical Recovery After Hospitalization (OPRAH study)
Scientific title	The efficacy of a blended intervention to improve physical activity and protein intake for optimal physical recovery after oncological gastrointestinal and lung cancer surgery: study protocol for a randomized controlled multicenter trial
Countries of recruitment	The Netherlands
Health condition(s) or problem(s) studied	Rehabilitation after oncological surgery
Intervention(s)	Intervention: Smartphone application and corresponding accelerometer in combination with coaching by a physiotherapist and dietician during three months after hospital discharge
	Control: Usual care
Key inclusion and exclusion criteria	Ages eligible for study: ≥ 18 years Sexes eligible for study: both Accepts healthy volunteers: no
	Inclusion criteria: adult patient (≥ 18 years), scheduled for curative intent surgery for gastrointestinal cancer, including esophageal and stomach cancer (upper GI), colorectal and hepato-pancreato-biliary (HPB) cancer, or lung cancer with a planned hospital stay of ≥ 2 nights, able to fill in online questionnaires in Dutch and give informed consent
	Exclusion criteria: pulmonary wedge resection, surgery with open/close procedure, having no access to a mobile device compatible for applications, less than 5 days between inclusion and surgery, patients who are wheelchair dependent, a Mini-Mental State Examination (MMSE) ≤ 24 and already participating in a conflicting study
Study type	Multicenter randomized controlled intervention trial with allocation at level of the individual
	Allocation: randomized
	Primary purpose: treatment
	Phase III trial
Date of first enrolment	June 2022
Target sample size	161
Recruitment status	Recruiting
Primary outcome(s)	Recovery in physical functioning six months after hospital discharge
Key secondary outcomes	Physical activity, lean body mass, pain, fatigue, muscle mass, protein intake, physical performance, patient-specific activity limitations, self-efficacy, participation in social roles and activities, generic quality of life, global perceived effect, hospital readmission and adverse events