Table 1.

Correlation between EZH2 and TOP2A expression and clinical characteristics in patients with HCC

Variables	Expression of EZH2		p	Expression of TOP2A		p
	High (n = 188)	Low (n = 187)		High (n = 188)	Low (n = 187)
Status			0.002*			0.042*
Alive	106	135		111	130
Dead	80	50		75	55
Age (years)			0.198			0.032*
Age Mean (SD)	58.5 (12.9)	60.3 (14.0)		57.9 (13.1)	60.9 (13.8)
Age Median [Min Max]	59 [18,85]	64 [16,90]		59 [18,85]	64 [16,90]
Gender			0.196			0.083
Male	67	54		69	52
Female	119	131		117	133
Grade of differentiation			0.000***			0.000***
G1	17	38		17	38
G2	78	99		73	104
G3	78	44		84	38
G4	10	2		9	3
Tumor invasion			0.002*			0.002*
T1	72	109		75	106
T2	59	35		55	39
T3	48	32		48	32
T4	7	6		8	5
TX		1			1
Lymph node status			0.345			0.264
N0	130	122		131	121
N1	3	1		3	1
NX	52	62		51	63
Distant metastasis			0.476			0.586
M0	137	129		135	131
M1	1	3		1	3
MX	48	53		50	51
TNM stages			0.024*			0.012*
I	69	102		15	38
II	51	35		56	55
III	53	32		82	68
IV	1	4		18	20

*p < 0.05, **p < 0.01, ***p < 0.001