Table 10.
Representative clinical trials of CAR-NKT therapies
| Clinical trials | Agents | Cancer types | Phase | Status |
|---|---|---|---|---|
| NCT03294954 | Anti-GD2 CAR and IL-15 expressing NKTs | Neuroblastoma | 1 | Active, not recruiting |
| NCT03774654 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
| NCT05487651 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
| NCT04814004 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
| NCT02439788 | Anti-GD2 CAR expressing NKTs | Neuroblastoma | 1 | Withdrawn |
CAR chimeric antigen receptor